Microbial Strain Development Scientist (EU024)


Nov 21st, 2022

Job Description

Handary leads the natural food shelf-life industry, sole expertise in preventing microbial spoilage, discoloration, off-flavor and nutrient loss during food storage. We designed and produced 26 well-known brands of natural shelf-life ingredients distributed worldwide. Currently, we look for 1 Microbial Strain Development Scientist in improving production yields of food antimicrobial strains in Belgium.

Tasks & Responsabilities:

  • Improve the production yields of industrial strains including Natamycin, Polylysine, Nisin and Lysozyme;
  • Bench-scale high cell density microbial fermentations toward optimization of bioprocess parameters such as media formulation and expression development;
  • Benchmarking studies focused on understanding strain performance and meeting project goals centered around titer, production rate, and yield metrics;
  • Construct and validate high-throughput, plate-based fermentation workflows for screening / characterization purposes and bioprocess development;
  • Develop technologies and/or methods oriented around strain adaptation/evolution
  • Optimization of fermentations and application of new technologies & strategies to accelerate and support scale-up efforts
  • Collaborate internally with the Strain Engineering, Analytics, and Process Development & Scale-up Groups as well as externally with Handary’s partners to guide strain development, fermentation work plans, and scale-up efforts
  • Establish a data management system to track fermentation-based data as well as implement statistical and computational analyses on large data sets
  • Lead the expansion and maintenance of the company’s fermentation capabilities: procurement of equipment, build-out, equipment troubleshooting & repair
  • Work with CMOs to facilitate the successful scale-up of in-house fermentation processes from the bench to commercial levels.


  • PhD or MS in Chemical Engineering, Biochemical Engineering, Fermentation Science, or a related discipline
  • PhD with 2+ years (or MS degree with 6+ years) of industrial/startup experience working directly with lab-scale and/or pilot-scale fermentations is required
  • Deep aptitude for & hands-on expertise with various aspects of fermentation R&D such as media design, fed-batch & chemostats operations, microaerobic & anaerobic fermentations, strain evolution studies, scale-down fermentation technologies (BioLector, Ambr), and high-throughput/automated culture development
  • Experience with implementing design of experiment (DoE) methods for strain screening/characterization and bioprocess development
  • Demonstrated success working both individually and cross-disciplinary to balance multiple independent experiments/projects
  • Solid fundamental knowledge of biochemical engineering principles including mass balance, mass transfer, reactor design, growth dynamics, and correlations between microbial physiology and fermentation/bioprocess performance
  • Familiarity with various bioreactor systems and control software; fermentation-related accessory technologies; and statistics, data analysis tools, and data management software
  • Excellent time management, experience managing engineers/technicians, and a keen sense for efficiently driving multiple projects in parallel
  • Ability and willingness to work extended days and weekends
Application Process
Qualified candidates must submit a resume, in Word or PDF format, along with a compelling cover letter that describes your interest in the position and why you think you would be a good fit for the job, as well as your salary expectation. Applications should be sent to:
[email protected]
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, age, national origin, disability, military status, genetic information, sexual orientation, or other applicable protected classes.

If you require alternative methods of application or screening, you must approach HANDARY directly to request this, as we're not responsible for the employer's application process.

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Brabant wallon
Brussels Hoofdstedelijk Gewest